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Software Solis Resto11/3/2022 The funders had no role in study design, data collection and analysis, decision to publish, or preparation of the manuscript.Ĭompeting interests: SGF is one of the founders of NovaDigm Therapeutics and serves on its scientific advisory board. The endothelial cells used in these studies were isolated from human umbilical cords, which were collected by the pediatric, perinatal and mobile unit of the UCLA Clinical and Translational Science Institute at LA BioMed/Harbor-UCLA Medical Center (UL1TR000124). National Institutes of Health grants (R01AI39108 to A.S.B., and R01AI054928 to S.G.F.). This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.įunding: This work was supported by grants of the Foundation for Research at the Medical Faculty, University of Zurich, Switzerland and Matching Funds of the Clinical Trials Center, University Hospital Zurich, Switzerland to K.S., the American Heart Association grants SDG 0630219N and GIA 09GRNT2180065 to Y.Q.X., and the U.S. Received: JanuAccepted: Published: June 22, 2012Ĭopyright: © 2012 Seidl et al. Munro, University of Aberdeen, United Kingdom (2012) Divergent Responses of Different Endothelial Cell Types to Infection with Candida albicans and Staphylococcus aureus. aureus interact with HMEC-1 cells in a substantially different manner than with HUVECs, and data obtained with one type of endothelial cell cannot necessarily be extrapolated to other types.Ĭitation: Seidl K, Solis NV, Bayer AS, Hady WA, Ellison S, Klashman MC, et al. aureus also induced little increase in IL-8 production above basal levels. This weak IL-8 response was likely due to the anatomic site from which HMEC-1 cells were obtained because infection of primary human dermal microvascular endothelial cells with C. In addition, HMEC-1 cells secreted very little IL-8 in response to infection with either organism, whereas infection of HUVECs induced substantial IL-8 secretion. albicans, but more susceptible to damage caused by S. Furthermore, HMEC-1 cells were less susceptible to damage induced by C. aureus adhered to and invaded HMEC-1 cells similarly to HUVECs, an agr mutant strain had significantly reduced invasion of HMEC-1 cells, but not HUVECs. albicans had significantly reduced adherence to and invasion of HMEC-1 cells as compared to HUVECs. aureus with endothelial cells in vitro, we compared the interactions of these organisms with HMEC-1 cells and HUVECs. To determine if HMEC-1 cells are suitable for studying the interactions of C. One candidate in this regard is HMEC-1, an immortalized human dermal microvascular endothelial cell line. The use of an immortalized endothelial cell line would obviate such difficulties. However, the use of HUVECs requires a constant supply of umbilical cords, and there are significant donor-to-donor variations in these endothelial cells. Numerous investigations have used human umbilical vein endothelial cells (HUVECs) to study microbial-endothelial cell interactions in vitro. #SOFTWARE SOLIS RESTO SOFTWARE#Using local restaurant pos systems no less quality than foreign-made software. One example is the restaurant software Solis Resto, which has been used by many restaurants and cafes, ranging from small to franchises. Indonesian-Made restaurant software is also relatively more affordable, so it will save more on POS investment in your restaurant.Endothelial cells are important in the pathogenesis of bloodstream infections caused by Candida albicans and Staphylococcus aureus. Choose the software modules according to your needs.Ĭonsider carefully the extent of your needs for operations in the restaurant. Do you need an inventory module? Do you need the additional modules offered? If so, then take the modules as needed, and if not you can buy them at a later date. Use custom-built touch screen hardware.ĬPU hardware with a custom-built touch screen monitor takes up more space than integrated hardware. However, if you have a limited budget and want to keep your costs as low as possible, then this option will save your hardware expenses significantly.Ĥ. Usually, a restaurant or cafe will put one or more mini printers to print out the menu from the frontliners. However, if you feel that your kitchen location is not too far away, then there is no need to put a mini printer in your kitchen, because the order form can be delivered manually without the need for a printout.īy doing this, of course you can save on hardware expenses for your mini printer.ģ. Do kitchens and bars really need printers? If later, over time you feel that one POS station is no longer adequate, then you can add another new station. This is considered to be more economical and less risky.
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